Leucomycin A1

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Leucomycin A1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

16846-34-7

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

化学性质

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	786
Cas No.	16846-34-7
Formula	C₄₀H₆₇NO₁₄
Synonyms	Kitasamycin A1,3-deacetyl Josamycin,Leucomycin V 4-isovalerate,9-dihydro Niddamycin,Turimycin H5
Solubility	Soluble in DMSO
Chemical Name	4^B-(3-methylbutanoate) leucomycin V
Canonical SMILES	O=C1C[C@H]([C@@H]([C@H]([C@H](C[C@H]([C@H](/C=C/C=C/C[C@H](O1)C)O)C)CC=O)O[C@@]2(O[C@@H]([C@H]([C@@H]([C@H]2O)N(C)C)O[C@]3(C[C@@](O)([C@H]([C@@H](O3)C)OC(CC(C)C)=O)C)[H])C)[H])OC)O
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Leucomycin A1, a major metabolite extracted from the leucomycin complex, is a major macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis.

Leucomycin A1 is one of the more potent members of leucomycin complex. Leucomycin complex (kitasamycin) is effective against a wide spectrum of pathogens, such as Gram-positive bacteria, Gram-negative cocci, mycoplasma, and Leptospira. Leucomycin complex has been used as an animal health product for control of Gram positive bacteria, Gram negative cocci, mycoplasma, and Leptospira. Until now, little is known about the activity of individual analogues within the complex. At a concentration of 1.56μg/ml, kitasamycin inhibited all isolates of Diplococcus pneumonia [2]. Each component of leucomycins potently inhibited the growth of Gram-positive bacteria and showed not so strong activity against the Gram-negative bacteria. Each component showed the same tendency towards the antibacterial spectrum [3].

References:
[1] Hata T, Sano Y, Ohki N, et al. Leucomycin, a new antibiotic[J]. The Journal of antibiotics, 1953, 6(2): 87-89.
[2] Balducci Y, BODEY G P. In vitro activity of kitasamycin against gram-positive cocci[J]. The Journal of antibiotics, 1974, 27(7): 516-519.
[3] Omura S, Katagiri M, Umezawa I, et al. Structure-biological activities relationships among leucomycins and their derivatives[J]. The Journal of antibiotics, 1968, 21(9): 532-538.