| 包装: | 10ug |
| 市场价: | 4410元 |
| Gene ID: | 654 | Accession #: | P22004 |
| Alternate Names: | Human BMP-6, BMP-6, BMP6, BMP 6, h-BMP-6, rh-BMP-6, recombinant human BMP-6, recombinant BMP-6, BMP | ||
| Source: | Escherichia Coli. | M.Wt: | monomer (15 kDa), dimer (30 kDa) |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Sterile filtered and lyophilized with no additives. | ||
| Solubility: | Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. | ||
| Shipping Condition: | gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Bone Morphogenetic Protein-6 (BMP-6) belongs to the transforming growth factor-β (TGFβ) superfamily related signaling proteins. Human recombinant BMP-6 produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain contains a mixture of multimers, dimer (30 kDa) and monomer (15 kDa). The dimer is an active polypeptide chain containing 2X142 amino acid residues. BMP-6 has been demonstrated to potently induce osteoblast differentiation in a variety of tissues such as eye, heart, kidney, skin, and other tissues.
| Determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells. | ||||||
| ED50 | =2-12 μg/ml. | |||||
| Specific activity | biologically active. | |||||
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