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MRS1186
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MRS1186图片
CAS NO:183721-03-1
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
MRS1186是人类腺苷A3受体(hA3AR)有效的、选择性拮抗剂,其Ki值为7.66nM。
Cas No.183721-03-1
Canonical SMILESCCC(NC1=NC2=C(C3=NC(C4=CC=CO4)=NN13)C=C(C=C2)Cl)=O
分子式C16H12ClN5O2
分子量341.75
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.

MRS1186 (compound 2d) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM[1].

[1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97.