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Rifampin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Rifampin图片
CAS NO:13292-46-1
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
1g电议
5g电议

产品介绍

化学性质

Physical AppearanceA solid
StorageStore at -20°C
M.Wt822.94
Cas No.13292-46-1
FormulaC43H58N4O12
Solubility≥26.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Canonical SMILESO[C@H]([C@H](C)[C@H]([C@H](/C=C/C=C(C)/C(NC1=C2O)=O)C)O)[C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O[C@@]3(C)OC4=C(C)C(O)=C2C(C(/C1=C/NN5CCN(C)CC5)=O)=C4C3=O)OC)OC(C)=O
运输条件蓝冰运输或根据您的需求运输。
一般建议为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Rifampicin is a bactericidal antibiotic drug of the rifamycin group.

试验操作

Animal experiment:[1]

Animal models

Male Parkes strain mice (20 ~ 25g) inoculated in the left hind footpad with 1 × 104viable units ofMycobacterium marinum(M. marinum)

Dosage form

0.003%, 0.01%, 0.03% and 0.1% rifampin in the diet

Administered by oral route

Applications

Rifampin at dosages of 0.003% and 0.01% in the diet was not suppressive to bacillary growth. A dosage of 0.03% resulted in a transient fall in viable bacillary count, which was followed by recovery of growth 10 days after inoculation. The highest dose (0.1%) was highly bactericidal, with the viable count ofM. marinumreduced to, and maintained below, the detectable level of 2.0 × 102organisms per foot pad after 7 days of treatment.

Note

The technical data provided above is for reference only.

References:

1. Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy, 1976, 22(3-4): 242-252.