化学性质
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 718.08 |
| Cas No. | 850140-73-7 |
| Formula | C32H33ClFN5O11 |
| Synonyms | BIBW 2992MA2;BIBW-2992;BIBW2992;BIBW 2992;Afatinib |
| Solubility | ≥35.9 mg/mL in DMSO; ≥147.2 mg/mL in H2O; ≥6.39 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | (Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
| Canonical SMILES | CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.
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