CAS NO: | 1975976-24-9 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 1975976-24-9 |
Canonical SMILES | CC1(C)CC[C@]2(C(O)=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](OC(C=C)=O)CC[C@]5(C)[C@@]4([H])CC=C3[C@]2([H])C1 |
分子式 | C33H50O4 |
分子量 | 510.7 |
溶解度 | DMF: 30mg/mL,DMSO: 20mg/mL,Ethanol: 30mg/mL,Ethanol:PBS (pH 7.2) (1:40): 0.02mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid .1 It acts as an agonist at the 5-HT1A receptor in mouse hippocampal homogenates in a [35S]GTPγS binding assay (EC50 = 0.79 μM). It is also a selective inhibitor of MAO-A over MAO-B (IC50s = 48.8 μM and >100 μM, respectively). In mice, OAA (10 mg/kg) reduces immobility in the forced swim test and increases the number of crossings and time spent at the center in the open field test, indicating anti-depressant-like and anxiolytic activities. References |