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Scyllo-Inositol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Scyllo-Inositol图片
CAS NO:488-59-5
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Scyllo-Inositol 是一种淀粉样抑制剂,抑制 α-突触核蛋白聚集。Scyllo-Inositol 在体外可以稳定非纤维状无毒形式的淀粉样蛋白-β 肽 (amyloid-β),逆转阿尔茨海默病小鼠模型的认知缺陷,降低突触毒性和淀粉样斑块。
Cas No.488-59-5
别名鲨肌醇
Canonical SMILESO[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1O)O)O)O)O
分子式C6H12O6
分子量180.16
溶解度Water: 5 mg/mL (27.75 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and loweres amyloid plaques in an Alzheimer's disease mouse model[1].

[1]. Ibrahim T, et al. α-Synuclein aggregation, seeding and inhibition by scyllo-inositol. Biochem Biophys Res Commun. 2016 Jan 15;469(3):529-34.