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2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide图片
CAS NO:529493-92-3
包装:100g
市场价:1945元

产品介绍
2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。
Cas No.529493-92-3
分子式C14H19BrO9
分子量411.2
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562