Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A1266 | WYE-354 | MTOR inhibitor,potent,ATP-competitive and cell-permeable | mTOR | 1062169-56-5 | COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5 |
A1933 | Carfilzomib (PR-171) | Proteasome inhibitor,epoxomicin analog | Proteasome | 868540-17-4 | CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4 |
A3019 | AT-406 (SM-406) | IAP inhibitor | IAP | 1071992-99-8 | CC(CC(N(C[C@@](/N=C(O)/[C@](NC)([H])C)([H])C1=O)CC[C@@](N21)([H])CC[C@@]2([H])/C(O)=N/C(C3=CC=CC=C3)C4=CC=CC=C4)=O)C |
A4007 | MLN9708 | Proteasome inhibitor | Proteasome | 1201902-80-8 | B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl |
A8323 | WP1130 | Deubiquitinase (DUB) inhibitor, Cell permeable | DUB | 856243-80-6 | CCCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N |
B1642 | WYE-125132 (WYE-132) | ATP-competitive mTOR inhibitor, highly potent | mTOR | 1144068-46-1 | CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7 |
B6099 | LY3023414 | class I PI3K isoforms, mTOR and DNA-PK inhibitor | PI3K | 1386874-06-1 | O=C(N(C1=C2C3=CC(C4=CC(C(O)(C)C)=CN=C4)=CC=C3N=C1)C)N2C[C@H](C)OC |
N1855 | Andrographolide | NF-κB signaling Inhibitor | IκB/IKK | 5508-58-7 | CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O |