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EDANS
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
EDANS图片
CAS NO:50402-56-7
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
EDANS(1,5-EDANS)是一种新型的淬灭荧光底物(fluorogenicsubstrate)，用于通过共振能量转移分析逆转录病毒蛋白酶。
Cas No.50402-56-7
别名5-(2-氨基乙氨基)-1-萘磺酸,1,5-EDANS
Canonical SMILESO=S(C1=C2C=CC=C(NCCN)C2=CC=C1)(O)=O
分子式C12H14N2O3S
分子量266.32
溶解度DMSO: 13.89 mg/mL (52.16 mM)
储存条件4℃, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1].

The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1].Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1].

[1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8.