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PDGF-BB,murine recombinant protein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PDGF-BB,murine recombinant protein图片
包装:10ug
市场价:4410元

产品介绍

描述

Gene ID:18591Accession #:P31240
Alternate Names:PDGFB, Murine PDGF-BB, m-PDGF-BB, PDGFBB, PDGF-BB, PDGF BB, rm-PDGF-BB, recombinant murine PDGF-BB, recombinant PDGF-BB, PDGF.
Source:Escherichia Coli.M.Wt:24.4 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in sterile 100mM acetic acid and 0.1% BSA to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). The PDGFs are stored in platelet α-granules, and are released upon platelet activation. PDGFs signals through receptors PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. However, PDGFR-β interacts with only PDGF-BB and PDGF-AB. PDGF-BB is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells and some blood cells.

Recombinant murine PDGF-BB is a homodimeric, non-glycosylated polypeptide of 109 amino acids and having a molecular mass of 24.4 kDa.

生物活性

Determined by the dose-dependent proliferation of murine BALB/c 3T3 cells.
ED50< 2 ng/ml.