您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > PDGF-AA,murine recombinant protein
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
PDGF-AA,murine recombinant protein
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
PDGF-AA,murine recombinant protein图片
包装与价格：
包装价格(元)
10ug电议
1mg电议

产品介绍

描述

Gene ID:18590Accession #:P20033
Alternate Names:PDGFA, Mouse PDGF-AA, h-PDGF-AA, PDGFAA, PDGF AA, PDGF-AA, rh-PDGF-AA, recombinant mouse PDGF-AA, recombinant PDGF-AA, PDGF.
Source:Escherichia Coli.M.Wt:28.9 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-0.5 mg/ml. This solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week and -20°C for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

The platelet-derived growth factor AA (PDGF-AA) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). The PDGFs are stored in platelet α-granules, and are released upon platelet activation. PDGFs signals through receptors PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. However, PDGFR-β interacts with only PDGF-BB and PDGF-AB. PDGF-AA is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells and some blood cells.

Recombinant mouse PDGF-AA is a disulfide linked non-glycosylated homodimer comprised of 2 polypeptide chains of 126 amino acids each, with a dimeric molecular weight of 28.9 kDa.

生物活性

Determined by the dose-dependent proliferation of Balb/c 3T3 cells and is typically 8 -10 ng/ml.