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SCF,murine recombinant protein
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
SCF,murine recombinant protein图片
包装与价格：
包装价格(元)
10ug电议
50ug电议
1mg电议

产品介绍

描述

Gene ID:17311Accession #:P20826
Alternate Names:Murine SCF, SCF, h-SCF, rh-SCF, recombinant human SCF, recombinant SCF.
Source:Escherichia Coli.M.Wt:18.3 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:SLyophilized from 10 mM Sodium Phosphate, pH 6.5.
Solubility:Reconstitute in sterile water to a concentration of 0.1-1 μg/μl. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor at the early stages of hematopoiesis. SCF promotes the survival, differentiation, and mobilization of myeloid, erythroid, megakaryocytic, lymphoid, germ cell and melanocyte progenitors. SCF exists in two forms: cell surface bound SCF and soluble SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.

 The murine SCF cDNA encodes a 273 aa protein contains a 25 aa signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. Human SCF shows low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is a 18.3 kDa protein containing 164 amino acid residues.

生物活性

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells.
ED50< 10 ng/ml.     
Specific activity> 1*105units/mg.