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Carpaine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Carpaine图片
CAS NO:3463-92-1
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Carpaine 番木瓜碱是一种从 Carica papaya Linn 中分离出的具有抗血小板减少活性的生物碱，在维持血小板数目方面表现出强烈的活性，无急性毒性。Carpaine 具有抗疟疾活性以预防疟疾。Carpaine 直接影响心肌，降低了大鼠的心脏血液输出量。Carpaine 因其心血管效应被研究。
Cas No.3463-92-1
别名番木瓜碱
Canonical SMILESO=C(CCCCCCC[C@@]1([H])N[C@@H](C)[C@@](CC1)([H])O2)O[C@](CC3)([H])[C@H](C)N[C@]3([H])CCCCCCCC2=O
分子式C28H50N2O4
分子量478.71
溶解度Chloroform: 10 mg/ml,DMF: 1,DMSO: 1 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity[1].Carpaine has anti-plasmodial activity to prevent malaria[2].Carpaine affects the myocardium directly, it reduces cardiac output, stroke volume, stroke work, and cardiac power in rat, which has been studied for its cardiovascular effects[3].

[1]. Zunjar V, et al. Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats. J Ethnopharmacol. 2016 Apr 2;181:20-5. [2]. Julianti T, et al. Quantification of the antiplasmodial alkaloid carpaine in papaya (Carica papaya) leaves. Planta Med. 2014 Aug;80(13):1138-42. [3]. Hornick CA, et al. Effect of carpaine, a papaya alkaloid, on the circulatory function in the rat. Res Commun Chem Pathol Pharmacol. 1978 Nov;22(2):277-89.