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AGN 210676(Simenepag)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AGN 210676(Simenepag)图片
CAS NO:910562-15-1
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
AGN 210676 (Simenepag) 是一种选择性前列腺素 EP2 激动剂,从专利 US20070203222A1 化合物实施例 23 中提取,具有 5 nM 的 EC50。
Cas No.910562-15-1
别名Simenepag
Canonical SMILESO=C(C1=CC=C(COC[C@@H](CC2)N(C3=CC=C([C@@H](O)CCCCC)C=C3)C2=O)S1)O
分子式C23H29NO5S
分子量431.55
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].

[1]. Old, David W, et al. SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS. US20070203222A1.