化学性质
| Storage | Store at -20°C |
| M.Wt | 243.73 |
| Cas No. | 58020-43-2 |
| Formula | C12H18ClNO2 |
| Synonyms | 4-Hydroxytulobuterol;HOKU 81;HOKU81 |
| Solubility | Soluble in DMSO |
| Chemical Name | 4-[2-(tert-butylamino)-1-hydroxyethyl]-3-chlorophenol |
| Canonical SMILES | CC(C)(C)NCC(C1=C(C=C(C=C1)O)Cl)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
HOKU-81 is one of the metabolites of tulobuterol. Effects of HOKU-81 on isolated trachea and atria of guinea pigs were compared with those of various bronchodilators. HOKU-81 appears to be a potent and selective beta 2-stimulant with a slight inotropic action. HOKU-81 was approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs. This effect of HOKU-81 seems to be due to direct action on the adrenergic beta-receptor.
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