Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A4005 | RO4929097 | γ secretase inhibitor | Gamma Secretase | 847925-91-1 | CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O |
A4145 | TG101209 | JAK2/3 inhibitor | c-RET | 936091-14-4 | CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)N4CCN(CC4)C |
A5602 | SB525334 | (TGF-beta1) receptor inhibitor | TGF-βR1(ALK5) | 356559-20-1 | CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3 |
A8213 | KY 02111 | WNT signaling inhibitor | Wnt/β-catenin | 1118807-13-8 | COC1=C(C=C(C=C1)CCC(=O)NC2=NC3=C(S2)C=C(C=C3)Cl)OC |
A8249 | SB 431542 | ALK inhibitor | TGF-βR1(ALK5) | 301836-41-9 | C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
A8340 | Cyclopamine | Hedgehog (Hh) signaling Inhibitor | Hedgehog | 4449-51-8 | CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1 |
A8348 | LY2157299 | TGF-βR1 inhibitor,potent and selective | TGF-βR1(ALK5) | 700874-72-2 | CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N |
A8709 | SW033291 | 15-PGDH enzyme inhibitor | HSC | 459147-39-8 | NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21 |