氨力农 (Inamrinone) 是一种正性肌力血管扩张剂。
Cas No. | 60719-84-8 |
别名 | 氨力农; Inamrinone |
Canonical SMILES | NC1=CC(C2=CC=NC=C2)=CNC1=O |
分子式 | C10H9N3O |
分子量 | 187.2 |
溶解度 | DMF: 0.3 mg/ml,DMSO: 0.5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs. |