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8-Deoxygartanin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
8-Deoxygartanin图片
CAS NO:33390-41-9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
8-Deoxygartanin 是山竹果中的一种 prenylated xanthones。8-Deoxygartanin 是一种丁基胆碱酯酶 (BChE) 的选择性抑制剂。8-Deoxygartanin 具有抗疟原虫活性,对 Plasmodium falciparum W2 植株作用的 IC50 值为 11.8 μM。8-Deoxygartanin 能抑制 NF-κB (p65) 的活化,IC50 值为 11.3 μM。
Cas No.33390-41-9
Canonical SMILESC/C(C)=C\CC1=C(O)C(C/C=C(C)/C)=C(O)C(C(C2=CC=C3)=O)=C1OC2=C3O
分子式C23H24O5
分子量380.43
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE)[1]. 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum[2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM[3]. p65|11.3 μM (IC50)

[1]. Khaw KY, et al. Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies. Phytomedicine. 2014 Sep 25;21(11):1303-9. [2]. Ngouamegne ET, et al. Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides. Chem Pharm Bull (Tokyo). 2008 Mar;56(3):374-7. [3]. Han AR, et al. Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). J Nat Prod. 2009 Nov;72(11):2028-31.