您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > 4'-O-Methylbavachalcone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
4'-O-Methylbavachalcone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4'-O-Methylbavachalcone图片
CAS NO:20784-60-5
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
4'-O-Methylbavachalcone 是从补骨脂中分离得到的查尔酮类,可抑制严重急性呼吸综合征冠状病毒 (SARS-CoV) 木瓜样蛋白酶 (PLpro) 的活性,IC50 值为 10.1 μM。
Cas No.20784-60-5
别名4'-O-甲基补骨脂查尔酮
Canonical SMILESO=C(C1=CC(C/C=C(C)\C)=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2
分子式C21H22O4
分子量338.4
溶解度DMSO: 50 mg/mL (147.75 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1]. IC50: 10.1 μM (PLpro)[1]

[1]. 4'-O-Methylbavachalcone, et al. Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. J Enzyme Inhib Med Chem. 2014 Feb;29(1):59-63.