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&beta3-AR agonist 2
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
&beta3-AR agonist 2图片
CAS NO:340757-05-3
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
β3-ARagonist2是一种有效的选择性β3肾上腺素能受体(β3-adrenergicreceptor，β3-AR)激动剂，EC50为8nM。
Cas No.340757-05-3
Canonical SMILESCC(C)C[C@@H](C(O)=O)NC(C1=CC=C(N2CCC(NC[C@H](O)C3=CC=C(O)C(NS(=O)(C)=O)=C3)CC2)C=C1)=O
分子式C27H38N4O7S
分子量562.68
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM.

β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 receptor[1].

β3-AR agonist 2 (Compound 26e) has significant thermogenesis effects on human β3-adrenergic receptor transgenic mice. β3-AR agonist 2 acts as a potential drug for the treatment of human obesity and type II diabetes[1].

[1]. Hu B, et al. (4-Piperidin-1-yl)phenyl amides: potent and selective human beta(3) agonists. J Med Chem. 2001 Apr 26;44(9):1456-66.