化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 338.24 |
Cas No. | 1314241-44-5 |
Formula | C15H20BrN3O |
Solubility | insoluble in H2O; ≥52.4 mg/mL in EtOH with ultrasonic; ≥9.35 mg/mL in DMSO |
Chemical Name | (5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone |
Canonical SMILES | C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CN=C3)Br |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
UNC669 is a potent and selective MBT (malignant brain tumor) inhibitor with IC50 of 6 μM for L3MBTL1, 5- and 11-fold selective over L3MBTL3 and L3MBTL4.生物活性
Description | UNC669 is a potent antagonist of L3MBTL with IC50 values of 4.2 μM and 3.1 μM for L3MBTL1 and L3MBTL3, respectively. |
Targets | L3MBTL1 | L3MBTL3 | | | | |
IC50 | 4.2 μM | 3.1 μM | | | | |