| CAS NO: | 256922-53-9 |
| 包装: | 5mg |
| 市场价: | 2070元 |
| Cas No. | 256922-53-9 |
| 别名 | 2-丙基噻唑并[4,5-C]喹啉-4-胺,3M002 |
| Canonical SMILES | CCCC1=NC2=C(N=C3C=CC=CC3=C2S1)N |
| 分子式 | C13H13N3S |
| 分子量 | 243.33 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | TLR8 agonist. Induces production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs). Promotes maturation of monocyte-derived dendritic cells in combination with Poly(I:C) (Cat.No.4287). Gorden et al (2005) Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. J.Immunol. 174 1259 PMID:15661881 |Pang et al (2011) Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol. 12 55 PMID:21962237 |Spranger et al (2010) Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075. J.Immunol. 185 738 PMID:20511554 |
m.cnreagent.com