化学性质
Physical Appearance | A solid |
Storage | Store at RT |
M.Wt | 557.54 |
Cas No. | 1837-91-8 |
Formula | C6H6Br6 |
Solubility | insoluble in EtOH; insoluble in H2O; ≥8.22 mg/mL in DMSO with gentle warming |
Chemical Name | 1,2,3,4,5,6-hexabromocyclohexane |
Canonical SMILES | C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.