GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2D^bmolecules at the RMA-S (Db Kb) cell surface with a SC₅₀of 344 nM^[1].

GP(33-41) sensitizes MC57 and T2-D^bcells to lysis with ED₅₀s of 0.9±0.6 and 2.5±0.7 nM^[1].
The interaction between T cell receptors (TCR) and peptide-major histocompatibility complex (pMHC) antigens can lead to varying degrees of agonism (T cell activation), or antagonism. The P14 TCR recognises the lymphocytic choriomeningitis virus (LCMV)-derived peptide, GP(33-41) (KAVYNFATC), presents in the context of H-2D^[2].

1016.17

C₄₆H₆₉N₁₁O₁₃S

161928-86-5

Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys

KAVYNFATC

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.