As-358

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As-358

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2222042-47-7

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

As-358 对埃博拉病毒 (Ebola virus) 和马尔堡病毒 (Marburg virus) 具有抑制活性，IC₅₀分别为 47.5 μM 和 3.7 μM。

生物活性

As-358 has inhibitory effects againstEbola virusandMarburg virus, withIC₅₀s of 47.5 μM and 3.7 μM^[1].

IC₅₀& Target

IC₅₀: 47.5 μM (EBOV), 3.7 μM (MARV)^[1]

体外研究
(In Vitro)

As-358 (compound 3b) (0-500 μM; 10 days) exhibits inhibitory activities against EBOV and MARV^[1].
As-358 (0-100 μM; 48 hours) can inhibit WT-EboV-GP and mutant D522A-EboV-GP, with IC₅₀s of 1.7 and 2.2 μM, respectively^[1].

Cell Proliferation Assay

Cell Line:	Vero (infected with EBOV and MARV)^[1]
Concentration:	0-500 μM
Incubation Time:	10 days
Result:	Exhibited inhibitory activities against EBOV and MARV, with IC₅₀s of 47.5 ± 8.2 μM and 3.7 ± 1.7 μM, SI values of 9 and 118, respectively.

分子量

293.44

Formula

C₁₈H₃₁NO₂

CAS 号

2222042-47-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.