Salvinorin A carbamate is a potent κ-opioid receptor (KOR) full agonist that is almost as potent as salvinorin A with EC50 values of 6.2 and 4.5 nM, respectively, for activation of the human KOR to enhance binding of [35S]GTPγS.
| Cas No. | 858345-57-0 |
| Canonical SMILES | [H][C@@]12CC[C@@]([C@@]3([H])[C@@]1(C)C[C@@H](C4=COC=C4)OC2=O)(C)[C@H](C(OC)=O)C[C@H](OC(N)=O)C3=O |
| 分子式 | C22H27NO8 |
| 分子量 | 433.5 |
| 溶解度 | Acetonitrile: 1 mg/ml,DMF: 1 mg/ml,DMSO: 2 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Salvinorin A carbamate is a potent κ-opioid receptor (KOR) full agonist that is almost as potent as salvinorin A with EC50 values of 6.2 and 4.5 nM, respectively, for activation of the human KOR to enhance binding of [35S]GTPγS. The addition of a carbamate group to salvinorin A increases biological stability by decreasing deacetylation. |
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