| CAS NO: | 868747-45-9 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 生物活性 | Cantuzumab ravtansine (IMGN242; huC242-DM4), anADC, is a humanized monoclonal antibody, huC242, covalently linked via a disulfide bond to DM4 (DM4(HY-12454)). Cantuzumab ravtansine has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts[1][2]. |
| 体外研究 (In Vitro) | Cantuzumab ravtansine（huC242-DM4；5 天）在 CanAg 阳性 SNU16 胃癌细胞中表现出细胞毒性作用[2]。 |
| 体内研究 (In Vivo) | Cantuzumab ravtansine（huC242-DM4；静脉注射；3.4 mg/kg；单剂量）可使携带 N87 人胃肿瘤异种移植物的 SCID 小鼠的肿瘤完全消退，在低于 2 mg/kg 的剂量下观察到显着的肿瘤消退[1]。 |
| CAS 号 | 868747-45-9 |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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