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Dynamin inhibitory peptide TFA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dynamin inhibitory peptide TFA图片
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Dynamin inhibitory peptide TFA 竞争性地阻止了动力蛋白 (dynamin) 与两性纤维蛋白的结合，从而防止了内吞作用。Dynamin inhibitory peptide TFA 阻断多巴胺 D3对 GABAA受体的作用。
生物活性

Dynamininhibitory peptide TFA competitively blocks binding ofdynaminto amphiphysin, thus preventing endocytosis.Dynamininhibitory peptide TFA blocks the dopamine D3effect on GABAAreceptors[1].

体外研究
(In Vitro)

Dynamin inhibitory peptide TFA (50 μM) inhibits GABAAR endocytosis[1].

分子量

1235.27

Formula

C49H81F3N18O16

Sequence

Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro

Sequence Shortening

QVPSRPNRAP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

 ContentsAssign value
Acidic amino acidAsp (D), Glu (E), and the C-terminal -COOH.-1
Basic amino acidArg (R), Lys (K), His (H), and the N-terminal -NH2+1
Neutral amino acidGly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)0

3.  Recommended solution:

Overall charge of peptideDetails
Negative (<0)1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.