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Aminobenzenesulfonic auristatin E-d8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aminobenzenesulfonic auristatin E-d8图片
包装与价格:
包装价格(元)
1mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Aminobenzenesulfonic auristatin E-d8 是 Aminobenzenesulfonic auristatin E 氘代物。Aminobenzenesulfonic auristatin E 是抗体偶联药物的一部分。Aminobenzenesulfonic auristatin E 由细胞毒性微管蛋白修饰剂 Auristatin E 和 ADC linker Aminobenzenesulfonic 连接而成,具有抗肿瘤活性。
生物活性

AminobenzenesulfonicauristatinE-d8 is the deuterium labeled AminobenzenesulfonicauristatinE. AminobenzenesulfonicauristatinE is a drug-linker conjugate for ADC. AminobenzenesulfonicauristatinE has potent antitumor activity by usingAuristatinE (a cytotoxic tubulin modifier), linked via theADC linkerAminobenzenesulfonic[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

分子量

761.05

性状

Solid

Formula

C37H56D8N6O8S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)