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Y-27152
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Y-27152图片
CAS NO:127408-30-4
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
Y-27152 是 KATP (Kir6) 通道开放剂 Y-26763 的前药，是一种长效的 K+ 通道开放剂，具有较少的心动过速:对清醒状态的高血压大鼠和狗的抗高血压作用。
Cas No.127408-30-4
化学名N-(benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide
Canonical SMILESO[C@@H]1C(C)(C)OC2=C(C=C(C#N)C=C2)[C@H]1N(C(C)=O)OCC3=CC=CC=C3
分子式C21H22N2O4
分子量366.41
溶解度<9.16mg/ml in DMSO
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Y-27152, a prodrug of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state[1][2].

References:
[1]. Nakajima T, et al. Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J Pharmacol Exp Ther. 1992 May;261(2):730-6.
[2]. Fukunari A, et al. Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Eur J Pharmacol. 1997 Apr 4;323(2-3):197-204.