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ML233
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ML233图片
CAS NO:2080311-92-6
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
ML233 是一种非肽类高效 apelin 受体(APJ)激动剂 (EC50=3.7 μM)。ML233 是血管紧张素 1 (AT1) 受体选择性 >21 倍 (>79 μM).
生物活性

ML233 is a non-peptide based potentapelin receptor (APJ)agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)[1].

IC50& Target

EC50: 3.7 μM (Apelin receptor)[1]

体外研究
(In Vitro)

ML233 shows potentially significant binding against several other receptors, including the 5-HT1A, α2C adrenergic, and benzylpiperazine receptors and norepinephrine transporter. ML233 shows some toxicity (LC50=25.8 μM) toward human hepatocyctes[1].

分子量

359.44

Formula

C19H21NO4S

CAS 号

2080311-92-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.