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N-Boc-PEG7-alcohol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-Boc-PEG7-alcohol图片
CAS NO:1292268-13-3
包装:250mg
市场价:598元

产品介绍
N-Boc-PEG7-alcohol 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。N-Boc-PEG7-alcohol 可用于合成一系列 PROTAC 分子。N-Boc-PEG7-alcohol 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
Cas No.1292268-13-3
分子式C19H39NO9
分子量425.51
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Boc-PEG7-alcohol is a PEG/Alkyl/ether-basedPROTAC linkercan be used in the synthesis of PROTACs. N-Boc-PEG7-alcohol is a cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs)[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.