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Finasteride-d9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Finasteride-d9图片
CAS NO:1131342-85-2
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
MK-906-d9
产品介绍
Finasteride-d9 是 Finasteride 氘代物。Finasteride (MK-906) 是一种有效的竞争性 5α-还原酶 (5α-reductase) 抑制剂,对 II 型 5α-还原酶的IC50值为 4.2 nM。Finasteride 对 II 型 5α-还原酶的亲和力比对 I 型酶高约 100 倍。Finasteride 可用于研究前列腺增生 (BPH) 和雄激素性脱发。
生物活性

Finasteride-d9 is deuterium labeled Finasteride. Finasteride (MK-906) is a potent and competitive 5α-reductase inhibitor, with an IC50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

381.60

Formula

C23H27D9N2O2

CAS 号

1131342-85-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.