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15-keto Prostaglandin F2α
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15-keto Prostaglandin F2α图片
CAS NO:35850-13-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.35850-13-6
别名15-keto PGF2α
化学名9α,11α-dihydroxy-15-oxo-prosta-5Z,13E-dien-1-oic acid
Canonical SMILESO[C@H]1[C@H](/C=C/C(CCCCC)=O)[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C1
分子式C20H32O5
分子量352.5
溶解度100 mg/ml (from PGF2a) in DMF, 100 mg/ml (from PGF2a) in DMSO, 100 mg/ml (from PGF2a) in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone. [1] [2] 15-keto PGF2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively. [1] [2] 15-keto PGF2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.[3]

Reference:
[1]. Sorensen, P.W., Hara, T.J., Goetz, F.W., et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol. Reprod. 39(5), 1039-1050 (1988).
[2]. Moore, A., and Waring, C.P. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J. Exp. Biol. 199(Pt 10), 2307-2316 (1996).
[3]. Woodward, D.F., Williams, L.S., and Chen, J. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res. 21(6), 428-435 (1989).