N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone, a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes.
| Cas No. | 257892-31-2 |
| 别名 | N-去甲罗格列酮 |
| Canonical SMILES | O=C(C(S1)CC(C=C2)=CC=C2OCCNC3=NC=CC=C3)NC1=O |
| 分子式 | C17H17N3O3S |
| 分子量 | 343.4 |
| 溶解度 | DMF: 25 mg/ml,DMSO: 34 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.5 mg/ml,Ethanol: 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone. |
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