您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > Imipenem(hydrate)
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Imipenem(hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Imipenem(hydrate)图片
CAS NO:74431-23-5
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
亚胺培南（水合物）是硫霉素的稳定结晶衍生物，是一种抗生素，对广泛的革兰氏阳性和革兰氏阴性需氧和厌氧细菌具有优异的活性。
Cas No.74431-23-5
别名亚胺培南一水物; N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
Canonical SMILES[H][C@@]1([C@@]([H])([C@H](O)C)C2=O)N2C(C(O)=O)=C(SCCNC=N)C1.O
分子式C12H17N3O4S•H2O
分子量317.4
溶解度PBS (pH 7.2): 2 mg/ml
储存条件Store at -20°C,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3].

References:
[1]. Zhanel GG, et al. Imipenem and meropenem: Comparison of in vitro activity, pharmacokinetics, clinical trials and adverse effects. Can J Infect Dis. 1998 Jul;9(4):215-28.
[2]. Jacoby GA, et al. AmpC beta-lactamases. Clin Microbiol Rev. 2009 Jan;22(1):161-82.
[3]. Balibar CJ, et al. cwrA, a gene that specifically responds to cell wall damage in Staphylococcus aureus. Microbiology. 2010 May;156(Pt 5):1372-83.