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Helvolic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Helvolic Acid图片
CAS NO:29400-42-8
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Hevolic acid (Fumigacin) 是一种从 Xylaria sp 中分离出来的抗生素，对革兰氏阳性菌有活性。
Cas No.29400-42-8
别名煙麴黴酸,Fumigacin
Canonical SMILESCC(O[C@H]1C[C@]2(C)[C@@]3(C)C([C@@H](OC(C)=O)[C@@]4([H])[C@H](C)C(C=C[C@]4(C)[C@]3([H])CC[C@@]2([H])/C1=C(C(O)=O)\CC/C=C(C)/C)=O)=O)=O
分子式C33H44O8
分子量568.7
溶解度DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.