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FCCP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FCCP图片
CAS NO:370-86-5
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
理化性质和储存条件
Molecular Weight (MW) 254.17
Formula C10H5F3N4O
CAS No. 370-86-5
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: ≥ 100 mg/mL
Water:
Ethanol: ≥ 30 mg/mL
Chemical Name N-(4-(trifluoromethoxy)phenyl)carbonohydrazonoyl dicyanide
Synonyms FCCP; Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
SMILES Code N#C/C(C#N)=N/NC1=CC=C(OC(F)(F)F)C=C1
实验参考方法
In Vitro

In vitro activity: FCCP (5 μM) results in a concentration-dependent decrease in Aβ and APPsβ production in K695sw cells. FCCP inhibits processing of wild-type APP. FCCP does not alter cellular ATP levels at any of the concentrations measured. The effects of FCCP on APP catabolism are independent of secondary effects on oxidative phosphorylation or the result of reduced cell viability. FCCP (5 μM or 500 nM), baf A1, and NH4Cl induce changes in Tf-Tx and Tf-F cellular fluorescence in K695 cells. FCCP (200 nM) protects and enhances the follicle integrity in cat ovarian tissue during short-term in vitro culture. But FCCP does not appear to exert a beneficial or detrimental effect during ovarian tissue cryopreservation.


Kinase Assay:


Cell Assay:

In Vivo
Animal model
Formulation & Dosage
References