CAS NO: | 1410101-89-1 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | (R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator ofPDK1with anAC50value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1]. | ||||||||||||||||
IC50& Target | AC50: 1.8 μM (PDK1)[1] | ||||||||||||||||
体外研究 (In Vitro) | (R)-PS210 displays an AC50value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold[1]. | ||||||||||||||||
分子量 | 380.31 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H15F3O5 | ||||||||||||||||
CAS 号 | 1410101-89-1 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 230 mg/mL(604.77 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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