CAS NO: | 1513879-21-4 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
2mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | BQR-695 is aPI4KIIIβinhibitor withIC50s of 80 and 3.5 nM for humanPI4KIIIβandPlasmodiumvariant ofPI4KIIIβ, respectively. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PHOsh2to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function. BQR695 shows no evidence of toxicity against mature red blood cells (RBCs), induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines[2]. | ||||||||||||||||
分子量 | 352.39 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H20N4O3 | ||||||||||||||||
CAS 号 | 1513879-21-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(141.89 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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