您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Suberosin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Suberosin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Suberosin图片
CAS NO:581-31-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
20mg电议

产品介绍
Suberosin 可从Plumbago zeylanica 分离得到,具有抗炎和抗血凝的活性。Suberosin 可通过调节NF-AT 和NF-κB,抑制PHA-诱导的 PBMC细胞增殖并捕获细胞周期G1过渡到 S期。
Cas No.581-31-7
别名软木花椒素
Canonical SMILESO=C1C=CC2=CC(C/C=C(C)\C)=C(OC)C=C2O1
分子式C15H16O3
分子量244.29
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB[1][2].

[1]. Y-C Chen, et al. Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NF-jB. British Journal of Pharmacology (2007) 150, 298-312. [2]. Golfakhrabadi F, et al. Anticoagulant activity of isolated coumarins (suberosin and suberenol) and toxicity evaluation of Ferulago carduchorum in rats. Pharm Biol. 2014 Oct;52(10):1335-40.