nNOS Inhibitor I 是一种选择性和细胞渗透性 nNOS 抑制剂，Ki 为 120 nM。
| Cas No. | 357965-99-2 |
| Canonical SMILES | N=C(NCCC[C@H](N)CNCCN)N[N+]([O-])=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O |
| 分子式 | C8H21N7O2•3CF3COOH |
| 分子量 | 589.4 |
| 溶解度 | Water: 50 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | nNOS inhibitor I is a cell-permeable, selective inhibitor of nNOS (Ki = 120 nM). It displays >2,500-fold and 320-fold selectivity over eNOS and iNOS, respectively. It has been used in a rabbit model for cerebral palsy to prevent hypoxia-ischemia-induced death and to reduce the number of newborn kits exhibiting signs of cerebral palsy. |
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