Barzolvolimab (CDX 0159) 是一种人源化抗KITIgG1 单克隆抗体。Barzolvolimab 特异性并有效抑制 KIT 的激活。Barzolvolimab 可以减少慢性诱导性荨麻疹的皮肤肥大细胞和疾病活动。
生物活性 | Barzolvolimab (CDX 0159) is a humanized anti-KITIgG1monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria[1]. |
体外研究 (In Vitro) | Barzolvolimab 以高特异性和亚纳摩尔亲和力结合 KIT 的细胞外结构域,并变构抑制干细胞因子 (SCF) 的激活[1]。
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储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |