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MMP-9 Inhibitor I
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
MMP-9 Inhibitor I图片
CAS NO:206549-55-5
包装:500μg
市场价:1799元

产品介绍
Cas No.206549-55-5
Canonical SMILESCCN(CC)CC1=CC(C)=C(N(S(C2=CC=C(OC)C=C2)(=O)=O)CC3=CC=CC=C3)C(C(NO)=O)=C1
分子式C27H33N3O5S
分子量511.6
溶解度DMF: 20 mg/ml,DMSO: 25 mg/ml,Ethanol: 33 mg/ml,Ethanol:PBS (pH 7.2) (1:8): 0.11 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 µM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 µM.