CAS NO: | 2416716-62-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Androgen receptor-IN-2 is a potent and orally activeandrogen receptorinhibitor. Androgen receptor-IN-2 has antitumor activity against prostatecancer[1]. | ||||||||||||||||
IC50& Target | Androgen receptor[1] | ||||||||||||||||
体外研究 (In Vitro) | Androgen receptor-IN-2 (compound A109, androgen-induced PSA-Luciferase assay) inhibits androgen binding to androgen receptor with an IC50of 535 nM[1]. | ||||||||||||||||
体内研究 (In Vivo) | Androgen receptor-IN-2 (compound A109) (60 mg/kg, p.o.) induces partial regressions of tumor growth in NCG mice bearing LNCaP tumors[1].
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分子量 | 535.44 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C24H24Cl2N4O4S | ||||||||||||||||
CAS 号 | 2416716-62-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(93.38 mM;Need ultrasonic and warming) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |