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Sclerotiorin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sclerotiorin图片
CAS NO:549-23-5
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.549-23-5
别名核丛青霉素
Canonical SMILESO=C1C2=COC(/C=C/C(C)=C/[C@@H](C)CC)=CC2=C(Cl)C([C@]1(C)OC(C)=O)=O
分子式C21H23ClO5
分子量390.9
溶解度DMF: 30 mg/ml,DMF:PBS(pH7.2) (1:2): 0.3 mg/ml,DMSO: 20 mg/ml,Ethanol: 3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 µM. Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 µM),, inhibition of Grb2-Shc interaction (IC50 = 22 µM),, and antagonism of endothelin receptors (IC50 = 114 and 152 µM for human ETA and ETB, respectively).