CAS NO: | 1025684-60-9 |
包装 | 价格(元) |
10μg | 电议 |
25μg | 电议 |
50μg | 电议 |
100μg | 电议 |
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.
Cas No. | 1025684-60-9 |
别名 | RvD4 |
化学名 | 4S,5,17S-trihydroxy-6E,8E,10E,13E,15Z,19Z-docosahexaenoic acid |
Canonical SMILES | O[C@@H]([C@@H](O)CCC(O)=O)/C=C/C=C/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CC |
分子式 | C22H32O5 |
分子量 | 376.5 |
溶解度 | 50 mg/ml in DMF, 50 mg/ml Ethanol |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.[2][3] RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection. [3] With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.[3] It also promotes the clearance of apoptotic neutrophils by human fibroblasts.[3] Reference: |