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PCTR1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PCTR1图片
CAS NO:1810710-59-8
包装与价格:
包装价格(元)
10μg电议
25μg电议
50μg电议
100μg电议

产品介绍
PCTR1 是一种有效的单核细胞/巨噬细胞激动剂,在细菌感染期间调节关键的抗炎和促分解过程。
Cas No.1810710-59-8
Canonical SMILESCC/C=C\C[C@H](O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=C\C/C=C\C/C=C\CCC(O)=O
分子式C32H47N3O9S
分子量649.8
溶解度DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 1 mg/ml,Ethanol/H20 (95:5): 2 mg/ml,PBS (pH 7.2): 0.1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.