您好，欢迎来到试剂信息网！ [登录] [免费注册]
试剂信息网
发布求购
位置：首页 > 产品库 > N-Oleoyl Leucine
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
N-Oleoyl Leucine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-Oleoyl Leucine图片
CAS NO:136560-76-4
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.136560-76-4
Canonical SMILESCCCCCCCC/C=C\CCCCCCCC(N[C@@H](CC(C)C)C(O)=O)=O
分子式C24H45NO3
分子量395.6
溶解度DMF: 10 mg/ml,DMSO: 12 mg/ml,Ethanol: 12 mg/ml,Ethanol:PBS (pH 7.2) (1:4): 200 µ g/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro. N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity.